What is it?

The Lead and Zinc Protoporphyrin (LZPP) test is a blood test used to assess exposure to lead and zinc. These heavy metals can be harmful to the body, especially in children. The test measures the levels of lead and zinc protoporphyrin, which are byproducts of heme synthesis, a process involved in the production of red blood cells.

Who is it for?

This test is typically recommended for:

• Children: Lead exposure can have severe consequences for children’s development and cognitive function.
• Adults: Individuals exposed to lead or zinc through their occupation (e.g., construction, manufacturing) or environment.
• People with symptoms of lead or zinc poisoning: These may include fatigue, weakness, abdominal pain, constipation, and neurological problems.

Outcome:

Elevated levels of lead protoporphyrin in the blood generally indicate lead exposure. High levels of zinc protoporphyrin can suggest zinc toxicity or a deficiency in iron, copper, or vitamin B6.

Preparation:

Before taking the LZPP test, it’s essential to:

• Inform your healthcare provider about any recent exposure to lead or zinc.
• Avoid taking any medications that might interfere with the test results.
• Fast for at least 8 hours before the blood draw.

If you have concerns about lead or zinc exposure, consult with a healthcare professional to determine if the LZPP test is appropriate for you.

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